First-generation antihistamine-induced drowsiness and the CYP2D6 genotype
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چکیده
منابع مشابه
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The CYP2D6 enzyme metabolizes a quarter of all prescribed drugs, including codeine. Some individuals have multiple functional copies of the CYP2D6 gene, making them “ultrarapid metabolizers”. They are able to metabolize codeine to morphine more rapidly and more completely. As a result, even with normal doses of codeine, these individuals may experience the symptoms of morphine overdose, which i...
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ژورنال
عنوان ژورنال: Proceedings for Annual Meeting of The Japanese Pharmacological Society
سال: 2018
ISSN: 2435-4953
DOI: 10.1254/jpssuppl.wcp2018.0_po3-14-9